Article

Phosphorylation bar-coding of Free Fatty Acid receptor 2 is generated in a tissue-specific manner

2023-09-01

Abstract excerpt

Free Fatty Acid receptor 2 (FFA2) is activated by short-chain fatty acids and expressed widely, including in white adipocytes and various immune and enteroendocrine cells. Using both wild type human FFA2 and a Designer Receptor Exclusively Activated by Designer Drugs (DREADD) variant we explored the activation and phosphorylation profile of the receptor, both in heterologous cell lines and in tissues from transgen...

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Literature Corpus work: eedbeae4-57f4-5d2f-9fb7-48fdeb667206
DOI: 10.1101/2023.09.01.555873

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