Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphic Variation in FFA Receptors: Functions and Consequences.

Handbook of experimental pharmacology - 1 Jan 2017

Ichimura Atsuhiko

Abstract excerpt

Overfeeding of fat can cause various metabolic disorders including obesity and type 2 diabetes (T2D). Diet provided free fatty acids (FFAs) are not only essential nutrients, but they are also recognized as signaling molecules, which stimulate various important biological functions. Recently, several G protein-coupled receptors (GPCRs), including FFA1-4, have been identified as receptors of FFAs by various...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Energy Metabolism
Share to Fatty Acids, Nonesterified
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Receptors, Cell Surface

Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 27864678
DOI: 10.1007/164_2016_57

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphic Variation in FFA Receptors: Functions and Consequences.PMID 27864678Read ↗

Free Fatty Acid Receptors (FFARs) In Adipose: Physiological Role and Therapeutic OutlookSemantic proximity Read ↗

Minireview: The effects of species ortholog and SNP variation on receptors for free fatty acids.Semantic proximity Read ↗

Characterizing pharmacological ligands to study the long-chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4.Semantic proximity Read ↗

A Variant in ADIPOR2 Is Associated with Increased Free Fatty Acid Levels in Chinese Population.Semantic proximity Read ↗

Reduced Free Fatty Acid Receptor 4 Gene Expression is Associated With Extreme Obesity and Insulin Resistance in Children.Semantic proximity Read ↗

Variation in the FFAR1 gene modifies BMI, body composition and beta-cell function in overweight subjects: an exploratory analysis.Semantic proximity Read ↗

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.Semantic proximity Read ↗

Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor.Semantic proximity Read ↗

Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed.Semantic proximity Read ↗

Variants in the FFAR1 gene are associated with beta cell function.Semantic proximity Read ↗

Free fatty acid receptors: structural models and elucidation of ligand binding interactions.Semantic proximity Read ↗

FABP2 gene polymorphism and metabolic syndrome in elderly people of croatian descent.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.