Article
Minireview: The effects of species ortholog and SNP variation on receptors for free fatty acids.
Molecular endocrinology (Baltimore, Md.) - 1 Aug 2013
Hudson Brian D, Murdoch Hannah, Milligan Graeme
Abstract excerpt
Although it is widely assumed that species orthologs of hormone-responsive G protein-coupled receptors will be activated by the same endogenously produced ligand(s), variation in potency, particularly in cases in which more than 1 receptor responds to the same hormone, can result in challenges in defining the contribution of individual receptors in different species. This can create considerably greater issues...
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