Article
Global effects of identity and aging on the human sperm methylome
2023-03-24
Abstract excerpt
As the average age of fatherhood increases worldwide, so too does the need for understanding effects of aging in male germline cells. Molecular change, including epigenomic alterations, may impact off-spring. Age-associated change to DNA cytosine methylation in the cytosine-guanine (CpG) context is a hallmark of aging tissues, including sperm. Prior studies have led to accurate models that predict a man’s age base...
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Identifiers and source
- Literature Corpus work
- eeb32f24-a0f6-551d-ab1f-8d7bcc8f32a3
- DOI
- 10.1101/2023.03.21.533698