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Article

Paternal germ line aging: DNA methylation age prediction from human sperm

2017-11-16

Abstract excerpt

<h4>Background</h4> The relationship between aging and epigenetic profiles has been highlighted in many recent studies. Models using somatic cell methylomes to predict age have been successfully constructed. However, gamete aging is quite distinct and as such age prediction using sperm methylomes is ineffective with current techniques. <h4>Results</h4> We have produced a model that utilizes human sperm DNA methy...

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Literature Corpus work
86a85020-c8d8-5efb-a24e-6f4b67599276
DOI
10.1101/220764
Open publication

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Paternal germ line aging: DNA methylation age prediction from human spermDOI 10.1101/220764
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