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Article

Aging of blood can be tracked by DNA methylation changes at just three CpG sites

3 Feb 2014

Abstract excerpt

BACKGROUND: Human aging is associated with DNA methylation changes at specific sites in the genome. These epigenetic modifications may be used to track donor age for forensic analysis or to estimate biological age. RESULTS: We perform a comprehensive analysis of methylation profiles to narrow down 102 age-related CpG sites in blood. We demonstrate that most of these age-associated methylation changes are reversed...

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PMID: 24490752
DOI: 10.1186/gb-2014-15-2-r24

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