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Article

Paternal germ line aging: DNA methylation age prediction from human sperm

22 Oct 2018

Abstract excerpt

BACKGROUND: The relationship between aging and epigenetic profiles has been highlighted in many recent studies. Models using somatic cell methylomes to predict age have been successfully constructed. However, gamete aging is quite distinct and as such age prediction using sperm methylomes is ineffective with current techniques. RESULTS: We have produced a model that utilizes human sperm DNA methylation signatures...

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Share to Epigenetics and DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30348084
DOI: 10.1186/s12864-018-5153-4

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