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Update on Transplacental Transfer of IgG Subclasses: Impact of Maternal and Fetal Factors

11 Sept 2020

Abstract excerpt

Transplacental antibody transfer from mother to fetus provides protection from infection in the first weeks of life, and the four different subclasses of IgG (IgG1, IgG2, IgG3, and IgG4) have diverse roles in protection against infection. In this study, we evaluated concentrations and transplacental transfer ratios of the IgG subclasses in a healthy UK-based cohort of mother-cord pairs, and investigated...

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Identifiers

PMID: 33013843
DOI: 10.3389/fimmu.2020.01920

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