Article
Understanding Viral and Immune Interplay During Vertical Transmission of HIV: Implications for Cure.
Frontiers in immunology - 1 Jan 2021
Amin Omayma, Powers Jenna, Bricker Katherine M, Chahroudi Ann
Abstract excerpt
Despite the significant progress that has been made to eliminate vertical HIV infection, more than 150,000 children were infected with HIV in 2019, emphasizing the continued need for sustainable HIV treatment strategies and ideally a cure for children. Mother-to-child-transmission (MTCT) remains the most important route of pediatric HIV acquisition and, in absence of prevention measures, transmission rates range...
Topics
- Anti-HIV Agents
- Breast Feeding
- CD4 Antigens
- Coinfection
- Delivery, Obstetric
- Female
- Genotype
- HIV Infections
- HIV-1
- Host-Pathogen Interactions
- Humans
- Infant