Article

Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine

2022-02-18

Abstract excerpt

Coronavirus vaccines that are highly effective against SARS-CoV-2 variants are needed to control the current pandemic. We previously reported a receptor-binding domain (RBD) sortase A-conjugated ferritin nanoparticle (RBD-scNP) vaccine that induced neutralizing antibodies against SARS-CoV-2 and pre-emergent sarbecoviruses and protected monkeys from SARS-CoV-2 WA-1 infection. Here, we demonstrate SARS-CoV-2 RBD-scN...

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Literature Corpus work: ee96837f-4b81-550f-94fb-603cb90eb362
DOI: 10.2139/ssrn.4038516

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