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Article

Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine

23 Oct 2022

Abstract excerpt

Coronavirus vaccines that are highly effective against current and anticipated SARS-CoV-2 variants are needed to control COVID-19. We previously reported a receptor-binding domain (RBD)-sortase A-conjugated ferritin nanoparticle (scNP) vaccine that induced neutralizing antibodies against SARS-CoV-2 and pre-emergent sarbecoviruses and protected non-human primates (NHPs) from SARS-CoV-2 WA-1 infection. Here, we...

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PMID: 36274085
DOI: 10.1038/s41467-022-33985-4

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