Article

Breadth of SARS-CoV-2 Neutralization and Protection Induced by a Nanoparticle Vaccine

2022-01-28

Abstract excerpt

<h4>ABSTRACT</h4> Coronavirus vaccines that are highly effective against SARS-CoV-2 variants are needed to control the current pandemic. We previously reported a receptor-binding domain (RBD) sortase A-conjugated ferritin nanoparticle (RBD-scNP) vaccine that induced neutralizing antibodies against SARS-CoV-2 and pre-emergent sarbecoviruses and protected monkeys from SARS-CoV-2 WA-1 infection. Here, we demonstrate...

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Literature Corpus work: 2be96f9d-18ee-5f26-aab2-818b55acded2
DOI: 10.1101/2022.01.26.477915

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