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Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

2021-03-16

Abstract excerpt

Understanding the ability of SARS-CoV-2 vaccine-elicited antibodies to neutralize and protect against emerging variants of concern and other sarbecoviruses is key for guiding vaccine development decisions and public health policies. We show that a clinical stage multivalent SARS-CoV-2 receptor-binding domain nanoparticle vaccine (SARS-CoV-2 RBD-NP) protects mice from SARS-CoV-2-induced disease after a single shot,...

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Identifiers and source

Literature Corpus work
94268499-62b8-54b9-be27-25d8f169b03f
DOI
10.1101/2021.03.15.435528
Open publication

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Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccinesDOI 10.1101/2021.03.15.435528
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