Article

Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants

2021-03-27

Abstract excerpt

<h4>ABSTRACT</h4> Vaccines that induce potent neutralizing antibody (NAb) responses against emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are essential for combating the coronavirus disease 2019 (COVID-19) pandemic. We demonstrated that mouse plasma induced by self-assembling protein nanoparticles (SApNPs) that present 20 rationally designed S2GΔHR2 spikes of the ancestral Wuha...

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Literature Corpus work: 65d793f5-5f47-50f4-87c3-4494934f1fc4
DOI: 10.1101/2021.03.26.437274

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