Article

Control of subunit stoichiometry in single-chain MspA nanopores

2021-09-25

Abstract excerpt

<h4>ABSTRACT</h4> Transmembrane protein channels enable fast and highly sensitive electrical detection of single molecules. Nanopore sequencing of DNA was achieved using an engineered Mycobacterium smegmatis porin A (MspA) in combination with a motor enzyme. Due to its favorable channel geometry, the octameric MspA pore exhibits the highest current level as compared to other pore proteins. To date, MspA is the o...

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Literature Corpus work: ee761554-8406-5974-8720-1d1d75d25012
DOI: 10.1101/2021.09.25.461773

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