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Article

Single-molecule sensing of peptides and nucleic acids by engineered aerolysin nanopores.

Nature communications - 29 Oct 2019

Cao Chan, Cirauqui Nuria, Marcaida Maria Jose, Buglakova Elena, Duperrex Alice, Radenovic Aleksandra, Dal Peraro Matteo

Abstract excerpt

Nanopore sensing is a powerful single-molecule approach for the detection of biomolecules. Recent studies have demonstrated that aerolysin is a promising candidate to improve the accuracy of DNA sequencing and to develop novel single-molecule proteomic strategies. However, the structure-function relationship between the aerolysin nanopore and its molecular sensing properties remains insufficiently explored....

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Identifiers

PMID: 31664022
DOI: 10.1038/s41467-019-12690-9
PMCID: PMC6820719

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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