Article

Implementing Integrated Genomic Risk Assessments for Breast Cancer: Lessons Learned from the eMERGE Study

2025-05-23

Abstract excerpt

<h4>Objective</h4> To develop and implement a pipeline for integrated breast cancer risk assessment using the BOADICEA model within the eMERGE study, incorporating polygenic risk scores (PRS), monogenic variants, family history, and clinical factors. <h4>Materials and Methods</h4> A pipeline was deployed across ten eMERGE clinical sites, integrating data from REDCap surveys, PRS reports, monogenic reports, and p...

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Literature Corpus work: ee683527-d8e1-569a-9f96-2aa46c32fb78
DOI: 10.1101/2025.05.22.25328180

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