Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of Personalized Genetic Breast Cancer Risk Estimation With Polygenic Risk Scores on Preventive Endocrine Therapy Intention and Uptake.

Cancer prevention research (Philadelphia, Pa.) - 1 Feb 2021

Kim Julian O, Schaid Daniel J, Vachon Celine M, Cooke Andrew, Couch Fergus J, Kim Christina A, Sinnwell Jason P, Hasadsri Linda, Stan Daniela L, Goldenberg Benjamin, Neal Lonzetta, Grenier Debjani, Degnim Amy C, Thicke Lori A, Pruthi Sandhya

Abstract excerpt

Endocrine therapy is underutilized to reduce breast cancer incidence among women at increased risk. Polygenic risk scores (PRSs) assessing 77 breast cancer genetic susceptibility loci personalizes risk estimates. We examined effect of personalized PRS breast cancer risk prediction on intention to take and endocrine therapy uptake among women at increased risk. Eligible participants had a 10-year breast cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aromatase Inhibitors
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Counseling

Share to Genetic Loci

Share to Incidence

Share to Precision Medicine

Share to Risk Assessment

Source

Identifiers

PMID: 33097489
DOI: 10.1158/1940-6207.CAPR-20-0154

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of Personalized Genetic Breast Cancer Risk Estimation With Polygenic Risk Scores on Preventive Endocrine Therapy Intention and Uptake.PMID 33097489Read ↗

Integrating breast cancer polygenic risk scores at scale in the WISDOM Study: a national randomized personalized screening trial.Semantic proximity Read ↗

Breast Cancer Polygenic-Risk Score Influence on Risk-Reducing Endocrine Therapy Use: Genetic Risk Estimate (GENRE) Trial 1-Year and 2-Year Follow-Up.Semantic proximity Read ↗

Uptake of polygenic risk information among women at increased risk of breast cancer.Semantic proximity Read ↗

A clinical pilot study for personalized risk-based breast cancer screening utilizing the polygenic risk scoreSemantic proximity Read ↗

Breast cancer polygenic risk scores in the clinical cancer genetic counseling setting: Current practices and impact on patient management.Semantic proximity Read ↗

A clinical pilot study for personalized risk-based breast cancer screening utilizing a polygenic risk score.Semantic proximity Read ↗

Awareness, knowledge, and attitudes toward polygenic risk scores for breast cancer in multiethnic high-risk cohorts of women.Semantic proximity Read ↗

Prospective Evaluation of a Breast Cancer Risk Model Integrating Classical Risk Factors and Polygenic Risk in 15 Cohorts from Six CountriesSemantic proximity Read ↗

Breast cancer polygenic risk scores: A 12-month prospective study of patient reported outcomes and risk management behaviorSemantic proximity Read ↗

Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries.Semantic proximity Read ↗

Toward more personalized breast cancer risk assessment: The polygenic risk score.Semantic proximity Read ↗

Polygenic risk scores to refine Breast cancer screening and prevention strategies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.