Article

Bridging Genomics and Pharmacoepidemiology to Expand Treatment Options for Alcohol Use Disorder

2026-01-11

Abstract excerpt

Alcohol use disorder (AUD) is a chronic, relapsing condition and a major public health problem. However, few medications are approved to treat AUD, and those available show limited efficacy. Drug repurposing is a cost-effective strategy to identify novel therapeutic uses for existing medications. Here, we describe a pipeline that integrates genetic and electronic health record (EHR) data to identify and evaluate d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ee30bb58-77fa-58ec-9e1a-2c750cb92e9f
DOI: 10.64898/2026.01.09.26343615

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bridging Genomics and Pharmacoepidemiology to Expand Treatment Options for Alcohol Use DisorderDOI 10.64898/2026.01.09.26343615Read

Leveraging genetic data to investigate molecular targets and drug repurposing candidates for treating alcohol use disorder and hepatotoxicitySemantic proximity Read

Leveraging genetic data to investigate molecular targets and drug repurposing candidates for treating alcohol use disorder and hepatotoxicity.Semantic proximity Read

Integrative Analysis of Genetic, Genomic, and Phenotypic Data for Ethanol Behaviors: A Network-Based Pipeline for Identifying Mechanisms and Potential Drug Targets.Semantic proximity Read

Advances in Medications and Tailoring Treatment for Alcohol Use DisorderSemantic proximity Read

Identifying compounds to treat opiate use disorder by leveraging multi-omic data integration and multiple drug repurposing databasesSemantic proximity Read

Pharmacogenomics of Alcohol Response and AddictionSemantic proximity Read

Gene expression differences associated with alcohol use disorder in human brainSemantic proximity Read

Using genome-wide association results to identify drug repurposing candidatesSemantic proximity Read

Pharmacotherapy, pharmacogenomics, and the future of alcohol dependence treatment, part 1Semantic proximity Read

Pharmacotherapy, Pharmacogenomics, and The Future of Alcohol Dependence Treatment, Part 2Semantic proximity Read

Pharmaceutical Repurposing Strategies for Metabolic Disorders: Insights from Mendelian Randomization StudiesSemantic proximity Read

Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice.Semantic proximity Read