Article

Leveraging genetic data to investigate molecular targets and drug repurposing candidates for treating alcohol use disorder and hepatotoxicity

2019-10-04

Abstract excerpt

<h4>Background</h4> Novel treatments for alcohol use disorder (AUD) and alcohol-related liver disease (ALD) are greatly needed. Genetic information can improve drug discovery rates by facilitating the identification of novel biological targets and potential drugs for repurposing. <h4>Methods</h4> The present study utilized a recently developed Bayesian approach, Integrative Risk Gene Selector (iRIGS), to identif...

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Literature Corpus work: ef991a19-ddde-52b0-8c16-97b8e52ce688
DOI: 10.1101/791723

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