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Article

Leveraging genetic data to investigate molecular targets and drug repurposing candidates for treating alcohol use disorder and hepatotoxicity.

Drug and alcohol dependence - 1 Sept 2020

Gray Joshua C, Murphy Mikela, Leggio Lorenzo

Abstract excerpt

BACKGROUND: Novel treatments for alcohol use disorder (AUD) and alcohol-related liver disease (ALD) are greatly needed. Genetic information can improve drug discovery rates by facilitating the identification of novel biological targets and potential drugs for repurposing. METHODS: The present study utilized a recently developed Bayesian approach, Integrative Risk Gene Selector (iRIGS), to identify additional risk...

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Source

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Identifiers

PMID: 32652377
DOI: 10.1016/j.drugalcdep.2020.108155
PMCID: PMC7423741

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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