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Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic <i>Schistosoma mansoni</i>

2024-08-30

Abstract excerpt

Mass-drug administration (MDA) of human populations using praziquantel monotherapy has become the primary strategy for controlling and potentially eliminating the major neglected tropical disease schistosomiasis. To understand how long-term MDA impacts schistosome populations, we analysed whole-genome sequence data of 570 Schistosoma mansoni samples (and the closely related outgroup species, S. rodhaini) from ei...

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Literature Corpus work
ee26e197-750e-5e74-998b-92d9b6bf8c00
DOI
10.1101/2024.08.29.610291
Open publication

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Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic <i>Schistosoma mansoni</i>DOI 10.1101/2024.08.29.610291
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