TRPtracker: a community database for monitoring praziquantel sensitivity at TRPM _PZQ variants

Abstract excerpt

The anthelmintic praziquantel (PZQ) has been used for decades as the clinical therapy for schistosomiasis, and remains the only available drug. As a cheap and effective drug therapy for all human disease-causing Schistosoma species, usage of PZQ underpins mass drug administration strategies aimed at eliminating schistosomiasis as a public health problem by 2030. Concern over the potential emergence of resistance...

Topics

Open a Topic to create a Post that cites this publication.

• Drug Transport and Resistance Mechanisms
• Helminth infection and control
• Ion Channels and Receptors
• Malaria Research and Control
• Parasites and Host Interactions
• Research on Leishmaniasis Studies
• Trace Elements in Health
• Trypanosoma species research and implications

Identifiers and source

Literature Corpus work

a166be64-89cd-573e-882d-a499ea912fa0

DOI

10.1101/2025.08.27.671753