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Three models of vaccination strategies against cryptococcosis in immunocompromised hosts using heat-killed <i>Cryptococcus neoformans</i> Δ <i>sgl1</i>

2022-02-01

Abstract excerpt

Vaccines are one of the greatest medical accomplishments to date, yet no fungal vaccines are currently available in humans mainly because opportunistic mycoses generally occur during immunodeficiencies necessary for vaccine protection. In previous studies, a live, attenuated Cryptococcus neoformans Δ sgl1 mutant accumulating sterylglucosides was found to be avirulent and protected mice from a subsequent lethal i...

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Literature Corpus work
ee03942e-3dac-51c4-8f89-2ebae0f5653e
DOI
10.1101/2022.01.31.478598
Open publication

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