Article

Protection of mice against experimental cryptococcosis by synthesized peptides delivered in glucan particles

2021-11-13

Abstract excerpt

The high global burden of cryptococcosis has made development of a protective vaccine a public health priority. We previously demonstrated that a vaccine composed of recombinant Cryptococcus neoformans chitin deacetylase 2 (Cda2) delivered in glucan particles (GPs) protects BALB/c and C57BL/6 mice from an otherwise lethal challenge with a highly virulent C. neoformans strain. An immunoinformatic analysis of Cda2...

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Literature Corpus work: 139ddeb7-2b30-51f0-9d86-1c0395cc23a4
DOI: 10.1101/2021.11.12.468465

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