Article

Vaccine-Mediated Protection of Mice Against African and Asian Clinical Strains of <em>Cryptococcus neoformans</em>

2025-09-30

Abstract excerpt

Infections with strains of the Cryptococcus neoformans species complex are responsible for over 100,000 deaths per year, predominantly due to meningitis in immunocompromised individuals. Despite much research, there are no licensed fungal vaccines available. Most experimental cryptococcal vaccine formulations have been tested in preclinical models using laboratory strains of C. neoformans, particularly H99 and KN9...

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Literature Corpus work: c135780d-d289-5138-8d37-c654743e75b8
DOI: 10.20944/preprints202509.2563.v1

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