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Article

Complement regulates inhalation tolerance at the dendritic cell/T cell interface.

Molecular immunology - 1 Jan 2007

Köhl Jörg, Wills-Karp Marsha

Abstract excerpt

Pulmonary exposure to innocuous aeroallergens is a common event leading to inhalation tolerance. Distinct subsets of pulmonary dendritic cells (DC) and regulatory T cells (T(Reg)) play critical roles in mediating and maintaining such tolerance. In asthmatics, the same aeroallergens drive a maladaptive, Th2-biased immune response resulting in airway inflammation and airway hyper-reactivity. The mechanisms...

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Source

Identifiers

PMID: 16889830
DOI: 10.1016/j.molimm.2006.06.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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