Article

Integrative Mendelian Randomization approaches for therapeutic target prioritisation in immune-mediated diseases

2024-04-29

Abstract excerpt

<h4>Background: </h4> Immune-mediated diseases (IMD) encompass a wide range of autoimmune and inflammatory disorders with aetiology related to immune system dysfunction, signifying a disease area with great potential for drug repurposing. In this study, we employed the genetically informed Mendelian Randomization (MR) method with two distinct exposure types: immune blood cell abundance and protein quantitative tra...

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Literature Corpus work: ed77567c-b906-5d46-98da-64fb3f450a36
DOI: 10.1101/2024.04.27.24306475

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