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Article

Optimizing Mendelian Randomization for Drug Prediction: Exploring Validity and Research Strategies

2024-02-28

Abstract excerpt

<title>Abstract</title> <p>Mendelian randomization (MR) plays an increasingly important role in drug discovery, yet its full potential and optimized framework for accurately predicting drug targets have not been firmly established. This study aimed to evaluate the efficacy of multiple MR models in predicting effective drug targets and to propose the optimal selection of models and instrumental variables for MR an...

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Literature Corpus work
f4bb1a4e-76b6-567e-bb65-3369ec385c79
DOI
10.21203/rs.3.rs-3966011/v1
Open publication

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Optimizing Mendelian Randomization for Drug Prediction: Exploring Validity and Research StrategiesDOI 10.21203/rs.3.rs-3966011/v1
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