Article

Widespread pfhrp2/3 deletions and HRP2-based false-negative results in southern Ethiopia

2023-10-09

Abstract excerpt

<h4>Background: </h4> Rapid diagnostic tests (RDTs) have played a significant role in expanding case management in peripheral healthcare systems. Histidine-rich protein-2 (HRP2) antigen detection (RDT) is predominantly used to diagnose P. falciparum . However, the evolution and spread of P. falciparum parasite strains that have deleted HRP2/3 genes, causing false-negative results, have been reported. This study as...

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Literature Corpus work: ece258ea-def2-5598-acb1-82bcee2238d6
DOI: 10.21203/rs.3.rs-3404831/v1

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