Article

Lipopolymer Mediated siRNA Delivery Targeting Aberrant Oncogenes for Effective Therapy of Myeloid Leukemia

2023-07-31

Abstract excerpt

<title>Abstract</title> <p>In contrast to exploiting proteins as targets like most conventional drugs and tyrosine kinase inhibitors (TKI), that are rendered futile in the face of emerging drug resistance, RNA Interference (RNAi) exerts its therapeutic action towards disease-driving aberrant genes. To realize the potential of RNAi, the major challenge is to efficiently deliver the therapeutic mediator of RNAi, sm...

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Literature Corpus work: eccc6ddb-8952-5a94-85e8-57b15a348131
DOI: 10.21203/rs.3.rs-3201595/v1

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