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Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cells <i>in vitro</i>

2023-12-27

Abstract excerpt

Gene silencing through RNA interference (RNAi) is a promising therapeutic approach for a wide range of disorders, including cancer. Non-viral gene therapy, using specific siRNAs against BCR-ABL , can be a supportive or alternative measure to traditional chronic myeloid leukemia (CML) tyrosine kinase inhibitor (TKIs) therapies, given the prevalence of clinical TKI resistance. The main challenge for such approaches...

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Literature Corpus work
1dfbf053-d844-5b14-b5fe-1248582bbbd1
DOI
10.1101/2023.12.27.573407
Open publication

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Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic myeloid leukemia cells <i>in vitro</i>DOI 10.1101/2023.12.27.573407
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