Article

Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during cell growth arrest

2024-06-26

Abstract excerpt

Cellular senescence has been strongly linked to aging and age-related diseases. It is well established that the phenotype of senescent cells is highly heterogeneous and influenced by their cell type and senescence-inducing stimulus. Recent single-cell RNA-sequencing studies identified heterogeneity within senescent cell populations. However, proof of functional differences between such subpopulations is lacking. T...

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Literature Corpus work: ec8f3c6a-cdae-5e84-8e9b-30fe897eb42c
DOI: 10.1101/2024.06.22.600200

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