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Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence induction

7 Aug 2025

Abstract excerpt

Cellular senescence has been strongly linked to aging and age-related diseases. It is well established that the phenotype of senescent cells is highly heterogeneous and influenced by their cell type and senescence-inducing stimulus. Recent single-cell RNA-sequencing studies identified heterogeneity within senescent cell populations. However, proof of functional differences between such subpopulations is lacking....

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Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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PMID: 40778874
DOI: 10.18632/aging.206299

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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