Article
Age-associated vulval integrity is an important marker of nematode healthspan.
Age (Dordrecht, Netherlands) - 1 Dec 2016
Leiser Scott F, Jafari Gholamali, Primitivo Melissa, Sutphin George L, Dong Jingyi, Leonard Alison, Fletcher Marissa, Kaeberlein Matt
Abstract excerpt
Improving healthspan, defined as the period where organisms live without frailty and/or disease, is a major goal of biomedical research. While healthspan measures in people are relatively easy to identify, developing robust markers of healthspan in model organisms has proven challenging. Studies using the nematode Caenorhabditis elegans have provided vital information on the basic mechanisms of aging; however,...
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