Loss of intestinal nuclei and intestinal integrity in aging C. elegans.

doi:10.1111/j.1474-9726.2011.00713.x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Loss of intestinal nuclei and intestinal integrity in aging C. elegans.

Aging cell - 1 Aug 2011

McGee Matthew D, Weber Darren, Day Nicholas, Vitelli Cathy, Crippen Danielle, Herndon Laura A, Hall David H, Melov Simon

Abstract excerpt

The roundworm C. elegans is widely used as an aging model, with hundreds of genes identified that modulate aging (Kaeberlein et al., 2002. Mech. Ageing Dev.123, 1115-1119). The development and bodyplan of the 959 cells comprising the adult have been well described and established for more than 25 years (Sulston & Horvitz, 1977. Dev. Biol.56, 110-156; Sulston et al., 1983. Dev. Biol.100, 64-119.). However,...

Topics

Aging
Animals
Caenorhabditis elegans
Cell Nucleus
Cell Size
Intestines
Microscopy, Confocal
Microscopy, Electron, Transmission
Microvilli
Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 21501374
DOI: 10.1111/j.1474-9726.2011.00713.x
PMCID: PMC3135675

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics