Article

Autophagy-dependent gut-to-yolk biomass conversion generates visceral polymorbidity in aging <i>C. elegans</i>

2017-12-15

Abstract excerpt

Aging (senescence) is characterized by the development of numerous pathologies, some of which limit lifespan. Key to understanding aging is discovery of the mechanisms (etiologies) that cause senescent pathology. In Caenorhabditis elegans a major senescent pathology of unknown etiology is atrophy of its principal metabolic organ, the intestine. Here we identify a cause of not only this pathology, but also of yolk...

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Literature Corpus work: 37e69a84-062f-5640-88b8-a565b47b6168
DOI: 10.1101/234419

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