Article

Genomic determinants of metastatic organotropism and dissemination tempo across 3,368 lung cancers

2026-06-10

Abstract excerpt

<title>Abstract</title> <p>Genomic studies of organotropism in non-small cell lung cancer (NSCLC) have been cross-sectional and largely confined to point mutations, leaving the temporal sequence of organ involvement and the contributions of copy-number, fusion and co-mutation context under explored. We analyzed 3,368 stage IV NSCLC patients from MSK-CHORD, relating point mutations, copy-number alterations (CNAs),...

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Literature Corpus work: ebdb4f9e-c884-5c1e-bb92-3cdb8717fbb0
DOI: 10.21203/rs.3.rs-9943957/v1

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