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Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape

16 Nov 2021

Abstract excerpt

The emergence of SARS-CoV-2 variants threatens current vaccines and therapeutic antibodies and urgently demands powerful new therapeutics that can resist viral escape. We therefore generated a large nanobody repertoire to saturate the distinct and highly conserved available epitope space of SARS-CoV-2 spike, including the S1 receptor binding domain, N-terminal domain, and the S2 subunit, to identify new nanobody...

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Monoclonal and Polyclonal Antibodies Research
SARS-CoV-2 and COVID-19 Research
vaccines and immunoinformatics approaches

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34874007
DOI: 10.7554/elife.73027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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