Article
An alpaca-derived nanobody recognizes a unique conserved epitope and retains potent activity against the SARS-CoV-2 omicron variant
2022-12-27
Abstract excerpt
The SARS-CoV2 Omicron variant sub-lineages spread rapidly through the world, mostly due to their immune-evasive properties. This has put a significant part of the population at risk for severe disease and underscores the need for anti-SARS-CoV-2 agents that are effective against emergent strains in vulnerable patients. Camelid nanobodies are attractive therapeutic candidates due to their high stability, ease of la...
Topics
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- Animal Virus Infections Studies
- Antimicrobial Peptides and Activities
- Bacteriophages and microbial interactions
- Biochemical and Structural Characterization
- Monoclonal and Polyclonal Antibodies Research
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- da867fc1-a72a-5c40-9411-ca286cb28909
- DOI
- 10.1101/2022.12.27.521990
