Article

The SEM-4 transcription factor is required for regulation of the oxidative stress response in <i>Caenorhabditis elegans</i>

2020-04-23

Abstract excerpt

Oxidative stress causes damage to cells by creating reactive oxygen species (ROS) and the overproduction of ROS have been linked to the onset of premature ageing. We previously found that a brap-2 (BRCA1 associated protein 2) mutant significantly increases the expression of phase II detoxification enzymes in C. elegans. An RNAi suppression screen to identify transcription factors involved in the production of g...

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Literature Corpus work: eb50666d-41b6-5570-9171-571b09941d42
DOI: 10.1101/2020.04.22.055772

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