Article

ATP-binding cassette subfamily C (ABCC) transporter 1 (ABCC1) and 4 (ABCC4) independent of their drug efflux ability affects breast cancer biology

2019-01-01

Abstract excerpt

Breast cancer treatment has been a challenge to date, due in part to cancer cells acquiring drug resistance. One of the mechanisms by which resistance can occur is the overexpression of drug efflux pumps such as ATP-binding cassette, subfamily C (ABCC) transporter 1(ABCC1) and 4 (ABCC4), which are members of ABC transporters. Recently research has shown that these proteins may be implicated in cancer biology indep...

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Literature Corpus work: eb4f67b7-5134-54b7-bc9d-0b7d383d65fc
DOI: 10.48780/publications.aston.ac.uk.00041153

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