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Article

Role of the Drug Transporter ABCC3 in Breast Cancer Chemoresistance

12 May 2016

Abstract excerpt

Increased expression of ABC-family of transporters is associated with chemotherapy failure. Although the drug transporters ABCG2, ABCB1 and ABCC1 have been majorly implicated in cancer drug resistance, recent studies have associated ABCC3 with multi drug resistance and poor clinical response. In this study, we have examined the expression of ABCC3 in breast cancers and studied its role in drug resistance and...

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PMID: 27171227
DOI: 10.1371/journal.pone.0155013

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