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Long-term culture of fetal monocyte precursors <i>in vitro</i> allowing the generation of <i>bona fide</i> alveolar macrophages <i>in vivo</i>

2021-06-05

Abstract excerpt

<h4>ABSTRACT</h4> Tissue-resident macrophage-based immune therapies have been proposed for various diseases. However, generation of sufficient numbers that possess tissue-specific functions remains a major handicap. Here, we show that fetal liver monocytes (FLiMo) cultured with GM-CSF (also known as CSF2) rapidly differentiate into a long-lived, homogeneous alveolar macrophage (AM)-like population in vitro . CSF...

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Literature Corpus work
eaa6131a-3534-54ea-a3a6-75b52712ec82
DOI
10.1101/2021.06.04.447115
Open publication

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Long-term culture of fetal monocyte precursors <i>in vitro</i> allowing the generation of <i>bona fide</i> alveolar macrophages <i>in vivo</i>DOI 10.1101/2021.06.04.447115
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