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Integrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host–pathogen dynamics during <i>Aspergillus fumigatus</i> infection

2026-05-02

Abstract excerpt

Primary alveolar macrophages (pAMs) are essential for the rapid clearance of conidia and maintenance of pulmonary homeostasis. However, Aspergillus fumigatus remains the leading cause of invasive pulmonary aspergillosis in immunocompromised patients, and the mechanisms governing fungal clearance versus invasion remain poorly understood. Although, pAMs can be isolated from human donors, their broader application i...

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Literature Corpus work
0d635cea-cda7-5437-9b7a-3ce13fca45da
DOI
10.64898/2026.04.30.721838
Open publication

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Integrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host–pathogen dynamics during <i>Aspergillus fumigatus</i> infectionDOI 10.64898/2026.04.30.721838
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