Article
A critical guideline for controlling monocyte-derived macrophages phenotypes.
Frontiers in immunology - 1 Jan 2025
Moschetti Giorgia, Oliveri Doriana, De Matteis Valeria, Zaccaria Marta, Rondelli Diego, Griego Anna, Scarpa Edoardo, Rizzello Loris
Abstract excerpt
Macrophages (Mϕ) are an extremely heterogeneous and rapidly adapting set of innate immune cells that are scattered throughout all tissues in humans from mid-gestation onwards. Their original definition as key players in phagocytosis and defense against pathogens is too restrictive nowadays, as Mϕ are central to tissue homeostasis, repair, and complex immune regulations involving adaptive immunity. The Mϕ exhibit...
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