Article
Red death in Caenorhabditis elegans caused by Pseudomonas aeruginosa PAO1.
Proceedings of the National Academy of Sciences of the United States of America - 14 Apr 2009
Zaborin Alexander, Romanowski Kathleen, Gerdes Svetlana, Holbrook Christopher, Lepine Francois, Long Jason, Poroyko Valeriy, Diggle Stephen P, Wilke Andreas, Righetti Karima, Morozova Irina, Babrowski Trissa, Liu Donald C, Zaborina Olga, Alverdy John C
Abstract excerpt
During host injury, Pseudomonas aeruginosa can be cued to express a lethal phenotype within the intestinal tract reservoir-a hostile, nutrient scarce environment depleted of inorganic phosphate. Here we determined if phosphate depletion activates a lethal phenotype in P. aeruginosa during intestinal colonization. To test this, we allowed Caenorhabditis elegans to feed on lawns of P. aeruginosa PAO1 grown on high...
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