Back to search

Article

Low spatial structure and selection against secreted virulence factors attenuates pathogenicity in <i>Pseudomonas aeruginosa</i>

2018-01-19

Abstract excerpt

<h4>ABSTRACT</h4> Bacterial opportunistic pathogens are feared for their difficult-to-treat nosocomial infections and for causing morbidity in immunocompromised patients. Here, we study how such a versatile opportunist, Pseudomonas aeruginosa , adapts to conditions inside and outside its model host Caenorhabditis elegans , and use phenotypic and genotypic screens to identify the mechanistic basis of virulence e...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9f564605-35bf-5195-8888-73e8beac209b
DOI
10.1101/250845
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Low spatial structure and selection against secreted virulence factors attenuates pathogenicity in <i>Pseudomonas aeruginosa</i>DOI 10.1101/250845
Low spatial structure and selection against secreted virulence factors attenuates pathogenicity in Pseudomonas aeruginosa.Semantic proximity
Atypical BlaIR Two-Component System in <i>Pseudomonas aeruginosa</i> Regulates Virulence but not β-Lactam ResistanceSemantic proximity
<i>Pseudomonas aeruginosa</i> isolates co-incubated with <i>Acanthamoeba castellanii</i> exhibit phenotypes similar to chronic cystic fibrosis isolatesSemantic proximity
Host and antibiotic jointly select for greater virulence in <i>Staphylococcus aureus</i>Semantic proximity
A combination of phenotypic responses and genetic adaptations enables <i>Staphylococcus aureus</i> to withstand inhibitory molecules secreted by <i>Pseudomonas aeruginosa</i>Semantic proximity
Evolutionary trade-offs between antimicrobial resistance and virulence in <i>Pseudomonas aeruginosa</i>Semantic proximity
Experimental evolution of independent genetic pathways for resistance to <i>Pseudomonas aeruginosa</i> pathogenicity within the nematode <i>Caenorhabditis remanei</i>Semantic proximity
The social evolution of siderophore production in <i>Pseudomonas aeruginosa</i> is environmentally determinedSemantic proximity
Mapping genetic and phenotypic diversity of <i>Pseudomonas aeruginosa</i> across clinical and environmental isolation sitesSemantic proximity
Within-species control reveals novel immune response genes in <i>Caenorhabditis elegans</i>Semantic proximity
Genetic and virulence factors behind the success of high-risk Pseudomonas aeruginosa clones: insights from comparative genomics and an experimental infection modelSemantic proximity
Interplay among Resistance Profiles, High-Risk Clones, and Virulence in the Caenorhabditis elegans Pseudomonas aeruginosa Infection Model.Semantic proximity
Select a neighboring publication to make it the new centre.