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A non-classical mechanism of β-lactam resistance in Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) and its effect on virulence

2022-06-17

Abstract excerpt

Methicillin-Resistant Staphylococcus aureus (MRSA) are pathogenic bacteria that are infamously resistant to β-lactam antibiotics, a property attributed to the mecA gene. Recent studies have reported that mutations associated with the promoter region of pbp4 demonstrated high levels of β-lactam resistance, suggesting the role of PBP4 as an important non- mecA mediator of β-lactam resistance. The pbp4 promoter-...

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Literature Corpus work
3c45134a-a41c-527d-a1cb-391e8851d9fa
DOI
10.1101/2022.06.17.496612
Open publication

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A non-classical mechanism of β-lactam resistance in Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) and its effect on virulenceDOI 10.1101/2022.06.17.496612
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