Article

Gene expression imputation provides clinical and biological insights into treatment-resistant schizophrenia polygenic risk

2023-05-15

Abstract excerpt

<title>Abstract</title> <p>Treatment-resistant schizophrenia (TRS) is a complex phenotype with important implications in the clinical course of a disease that is both underdiagnosed and poorly treated. The identification of predictors and biomarkers for the early detection and treatment of TRS is a critical step. Large genome-wide association studies (GWAS) have revealed the polygenic nature of TRS. Gene expressi...

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Literature Corpus work: ea7d12cd-c062-55f6-8cb9-6557a3aad871
DOI: 10.21203/rs.3.rs-2922201/v1

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